Transpose 4th Newsletter

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    Marcello Lembo

    Dear WP Leaders,
    We kindly ask you to send us a brief text about your WP: what you did so far, what the next steps are and if there are events or news that you would like to share with Transpose members.
    Please, write here in this topic your text, within Friday, July 15th.
    Thank you in advance for your collaboration.
    Marcello and WP2 Team


    Christina Mikkelsen


    In the end of June 2019, the WP5 submitted their D.5.2 report on donor eligibility criteria and the D.5.3 report on guiding principles for donor selection. The first included all the 74 risk assessments performed by the WP5 members. We are now working on completing our three papers, two describing current risks to donors and recipients and one presenting the results of the TRANSPOSE recommendations for donor selection.
    The D.5.4 recommendations for donor selection is currently been reviewed and commented by both the TRANSPOSE Advisory Board as well as Collaboratory Stakeholders. We have also invited experts from other international organizations to comment, as well as members of the EDQM.
    The recommendations will be finalized in August and September, where our members will discuss the comments and suggestions received. The final version will be submitted by the end of September 2019.


    Sabrina Sandner


    At the end of June, we submitted the first validated draft of the standardized donor health questionnaire. To include potential donors in the validation, two different online studies were carried out in Germany and Austria and a total of 4,355 adults took part in the online survey. The first study is about the two main issues: Understanding the questions and the truthfulness of the answers. The second study deals with the version of the questionnaire (print vs. online), the arrangement of the questions (division by area vs. division by time) and with the question of the general state of health, i.e. “Are you feeling fit and well enough to donate” (at the beginning vs. at the end).
    We are currently in the process of implementing the opinion of experts from other international organizations so that we can provide a wide range of feedback in the donor health questionnaire.
    When the donor health questionnaire is finalized, it will be translated in the next step.




    The Coordinators of TRANSPOSE have been working on the Project Periodic Reporting for the TRANSPOSE as well as on other administrative and financial matters. We have additionally been preparing for the ISBT conference that took place in Basel in the end of June. TRANSPOSE was present at the conference with 3 presentations (Outcomes of the TRANSPOSE project, WP4 results, WP5 results) as well as a poster on the results of our risk assessments and recommendations.
    In the coming months, WP1 will be focused on supporting WP5 with finishing their final deliverables as well as WP6 with their questionnaire. Additionally, together with WP5, we are working on creating a special edition of publications with Vox Sanguinis.

    Since CNS and Sanquin took over the coordination of WP7, we have been working on organising the materials which have been created in the past 1,5 years of the TRANSPOSE project and defining what we will include in the training and workshop. A list of participants to the workshop has been created and will be refined in the coming months, and individuals will be contacted in the Autumn to be invited to the workshop taking place in Amsterdam March 2020.
    A timeline has been established indicating the action points to be carried out the coming months, therefore priority will be placed on preparations for the online training and the workshop.

    WP4 has completed its tasks in late 2018. The WP4 has drawn up an inventory
    of all current practices in donor selection and protection and then gather knowledge
    and expert opinions about benefits and pitfalls of specific practices.
    In 2017-2018, the WP4 team completed the practices recollection on different substances
    of human origins (SoHO’s): plasma, stem cells, blood, tissues and Assisted Reproductive
    Technology (ART).
    WP4 then created questionnaires for any SoHO’s sub-groups and sent them out
    for feedback to a group of experts. This information has been put in a database and
    thoroughly discussed along with WP5 and WP6 members in September 2018. They have
    since completed writing their report of the inventory they put together.
    This report has been refined and will soon be submitted as a scientific article with Vox Sanguinis. In addition, the results of this WP have been presented at the ISBT Conference in Basel, 22-26 June 2019.

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